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In addition, it could alter the epigenetic and metabolomic profiles of cancer cells and could eradicate cancer stem cells by activating ten-eleven translocation proteins (TETs) and suppressing pluripotency [74]

10.3390/ijms20163892 Int J Mol Sci

Figure 2 As shown in Figure 2B , G6PD silencing in mock-infected cells induced a decrease of GSH/GSSG ratio (~40% decrease) compared to mock control siRNA cells