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This shows that hypertension leads to iron overload in the brain, and iron overload increases OS and lipid peroxidation, thereby causing ferroptosis (Yang et al., 2020) in neurons and ultimately leading to brain injury (Figure 2)

Polyethylene glycol-based polymer-drug conjugates: novel design and synthesis strategies for enhanced therapeutic efficacy and targeted drug delivery

A review of dietary polyamines: Formation, implications for growth and health and occurrence in foods

Trial sequential monitoring boundaries and required sample size were quantified by setting type I error at 5% and power of 80% along with relative risk reduction of 60% for dialysis-related hypotension and 57% for muscle cramps based upon results after excluding high-risk trials