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However, analysis of mutants in the OASTL revealed that the Cys synthesis can be restricted to a single compartment without affecting survival and with only small effects on growth (Watanabe et al., 2008

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When patients with JakobCreutzfeldt disease underwent PET imaging with [ 11 C] d-l-deprenyl and [ 18 F]fluorodeoxyglucose ([ 18 F]FDG), increased astrogliosis and decreased cerebral glucose metabolism were observed in the frontal, occipital and parietal cortices and cerebellum 351,352

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