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[20] For nutritional deficiency without intrinsic-factor loss, shorter courses-such as 30-100 mcg intramuscularly daily for five to ten days followed by 100-200 mcg monthly-are often sufficient

A daily vitamin D supplement is commonly recommended during the preconception period, particularly in the UK where sunlight is limited for much of the year

Though the evidence base is limited to a small number of case reports, those with known cobalt allergy are advised to discuss B12 supplementation with a clinician before starting (MHRA, 2023)

Vitamin B12 status is typically assessed by measurements of serum or plasma vitamin B12 levels