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These processes are damaged under oxidative stress and by other pathophysiological factors in a variety of diseases and conditions, resulting in faulty signaling and disrupted signal conduction, which in turn leads to PN symptoms [10,12]

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Benefits from better peptide resolution in multiplexed LC outweighed the potential for sample loss and dilution effects introduced through fractionation and concatenation

this is of potential importance not only for the understanding of ASD pathogenesis but also for supporting the diagnosis of ASD and monitoring the disease progression