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gnavus abundance demonstrates nephrotrophic pathological predisposition, correlating positively with systemic inflammatory cascades, dysregulated inflammatory immune cell differentiation patterns, and autoantibody concentrations, while multi-strain Lactobacillus therapeutic intervention facilitates intestinal barrier restoration in LN murine models (Nepal and Gazeley, 2023

The combination of N-terminal amine, histidine at position 2, and intervening amide nitrogen is a recurrent high-affinity copper-binding motif in peptide biochemistry the same general motif also appears in human serum albumin's N-terminal copper-binding site