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doi: 10.1177/030098589603300506

Any intervention that might improve muscle preservation has proportionally greater value in this population, even if the absolute effect is modest

Conversely, under iron-depletion conditions, cluster disassembly exposes its RNA-binding domain, enabling it to bind IRE-containing mRNAs to promote iron uptake and release, by enhancing TFRC expression and inhibiting ferritin expression, respectively