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10.1016/j.freeradbiomed.2011.02.032 28 DongL.-F.LowP.DyasonJ

Lowering homocysteine levels by supplementing with B vitamins has been shown to reduce the rate of brain atrophy in elderly people with mild cognitive impairment.[ref] Researchers have found that high homocysteine exacerbates amyloid-beta-induced cell death in the brain.[ref] Osteoporosis: Researchers think the connection between high homocysteine and osteoporosis could be due to dysregulation of the transsulfuration pathway rather than a problem with the remethylation of homocysteine

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30 It also should be noted that other agents that are not drugs also can cause hemolysis in G6PD-deficient individuals