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Deu@PEPS exhibited a lower intensity of green fluorescence compared with control group, confirming the ability of the SPMs to obliterate excessive ROS in psoriatic keratinocytes ( Additional file 1: Figure S4 )

Determinants of activity in glutaredoxins: an in vitro evolved Grx1-like variant of Escherichia coli Grx3

The permeability transition pore (mPTP) in the mitochondrial membrane develops in response to Ca 2+ overload and enables the release of pro-apoptotic factors