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A higher percentage of participants in the pramlintide groups achieved a weight loss of at least 10% at the 12-month mark compared to the placebo group (40% and 43% vs

1 The prevalence is 70% in Kenyan school children, 80% in East Indian preschool-aged children, and 70% in East Indian adults

OCT1 Expression in adipocytes could contribute to increased metformin action in obese subjects

It is posited that through these receptors, the peptide may encourage fat burning in adipose tissue and foster 'thermogenesis' in skeletal muscle cells