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interleukin-6 (IL6), plasminogen activator inhibitor 1 (PAI1), and NAD(P)H dehydrogenase [quinone] 1 (NQO1), respectively

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10.1038/npp.2015.369 53 BianchiR.ChuangS

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In this reaction, homocysteine is remethylated to methionine, which is necessary for protein synthesis, through catalysis by MS, which requires B12 as a cofactor and employs 5-methyltetrahydrofolate produced by MTHFR as the methyl group donor (21)

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Therefore, maintaining an appropriate balance of ROS is crucial for ensuring male reproductive health

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