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Proteins such as G protein-coupled receptors, PI3K, AKT, MMPS, EGFR, VEGF, ERK, STAT3, p53, FOX, JNK, caspases, JAK, PKC, FGF, Nrf2, ALK, ROS1, mTOR, and MAPK are pivotal derivers in the pathogenesis of human cancers (386, 392)

Our data indicate that HIV infection of human macrophages results in significant accumulation of lipids in the macrophages that survive HIV infection, especially in the fused macrophages (Fig