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KO of Sb9 in mesenchymal stem cells (MSCs) results in diminished activity of downregulating cytotoxic T lymphocyte (CTL)-mediated lysis, suggesting that Sb9 in MSCs could be a potential target due to its immunosuppressive properties ( 4.4 Serpinb9 in other diseases and conditions Sb9 may play a multifaceted role in HIV treatment

Cell Mol Life Sci 72:13311345 Sadoshima J, Montagne O, Wang Q, Yang G, Warden J, Liu J, Takagi G, Karoor V, Hong C, Johnson GL, Vatner DE, Vatner SF (2002) The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy