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Based on this, we propose a model for disturbed red cell maturation in PKD that suggests that the main problem in PKD may not only be the PK-deficient erythrocyte, but for it to reach the mature red cell state

Intercellular communication plays an important role in tissue homeostasis, and gap junctions between hepatocyte are important guardians of this process

In published preclinical research, BPC-157 has been administered at doses ranging from 6 to 50 micrograms per kilogram body weight in animal models, with most tissue-repair and gastric-protection protocols using 10 to 20 mcg/kg once or twice daily (PMID 21030672, PMID 32558293, PMID 38980576)

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