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Beyond sleep, researchers have studied DSIP for its effects on stress hormone regulation specifically its ability to modulate ACTH and cortisol secretion making it of interest in HPA axis research

Despite forming an $80B market, many compounds remain unapproved

Such an indication is unique from most other drugs and compounds identified by the NIA-supported Intervention Testing Program (ITP) to improve lifespan, as acarbose, 17--estradiol, nondihydroguaiaretic acid (NDGA), and protandim, all preferentially improve male lifespan 35,36

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