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It has been shown that ibuprofen can induce ferroptosis in glioblastoma cells by inhibiting the expression of GPX4 and solute carrier family 7 member 11 (SLC7A11) through inhibition of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway (45)

Building upon this, Mendelian randomization (MR), a causal inference method based on genetic variation, can effectively overcome confounding and reverse causation issues commonly seen in observational studies

Cohen serves on several Scranton area boards, including Scranton Tomorrow, Valley in Motion and First Friday

[DOI] [PubMed] [Google Scholar] 167.Larrieu T., Cherix A., Duque A., Rodrigues J., Lei H., Gruetter R., Sandi C