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Running coach Steve Magness called the Bulletproof Diet bogus on his Science of Running blog in 2014, arguing that whatever benefits Asprey claims hes experienced from his coffee and nutrition plan come from his use of testosterone, nootropics, and thyroid medication

Baar et al., FOXO4-DRI reduced the lifespan of primary human fibroblasts IMR90 induced into senescence by ionizing radiation by over 11 times (11.73 times), compared to the control group consisting of non-senescent IMR90 cells [127]