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This vitamin is also necessary for producing the chemical serotonin, which works as a mood regulator, so having an increased or healthy amount of vitamin B12 will also boost mood

With b12 deficiency there can be an enlargement of red blood cells called macrocytiosis

Regarding cardiac risk, the lorcaserin group was non-inferior to the placebo group with slightly better values in cardiac risk factors (blood pressure, heart rate, glycemic control, lipid profile)