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The main concern is stacked GI side effects - both compounds slow digestion through different pathways, so combining them can amplify nausea, vomiting, and constipation

Injection-Related Risks : Injectable BPC-157 carries risks linked to nonsterile preparation, dosing errors, local infection, irritation, and improper administration

One sublingual-specific consideration: niacinamide can cause flushing (warmth and redness in the face and upper body) in some people, and sublingual absorption may increase the likelihood of flushing compared to injectable because the niacinamide enters the bloodstream more rapidly

It's important to note that individual results will vary