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After the first developed PARP inhibitor, olaparib, multiple PARP inhibitors such as niraparib, veliparib, and talazoparib were subsequently developed and tested in different phases of clinical trials

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Markers of HBV Infection and CHB Disease Progression The progression of CHB depends on the interaction between the virus and the host's immune response, with the main morbidity burden resulting from long-term liver complications (cirrhosis and HCC) that can develop as a result of a persistent immune response against HBV-infected hepatocytes