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These findings are supported by a recent integrative review of the literature (Kutcher 2022) and a meta-analysis (Yeh 2024) that concluded that acupuncture can improve symptoms of CIPN, pain, and quality of life for affected patients

Excessive autophagy can lead to metabolic stress and degradation of cellular components, which exacerbates the structural destruction and functional decline of tissues ( 2 O 2 -induced autophagy with a decreased expression of autophagy marker proteins LC3-II and Beclin-1