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Description

Daptomycin versus standard therapy for bacteremia and endocarditis caused bystaphylococcus aureus

GPx1 is one of the most critical members of the GPxs family that catalytically reduces hydrogen peroxide to produce water

In this form the sulfate of P-APS is reduced to sulfite by the free thiol (reduced) group of Sulfur Assimilation The reduced sulfur is finally transferred from the carrier to O-acetylserine (OAS) forming cysteine : O-acetylserine + H2S (or carrier-S-S-) cysteine + acetate The OAS is formed from serine and acetyl-CoA: serine + acetyl-CoA O-acetylserine + CoA This whole process is illustrated as follows: This is summarized in Fig