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Oxidation of the solvent-exposed W32 residue in SOD1 in particular has been associated with aggregation of mutant SOD1 in vitro and in vivo (Taylor et al., 2007

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His perception of light was present

Mer3/HFM1 is a SF2 helicase, and is structurally related to RNA helicases including Brr2 26 and Mtr4 27 , which contain a helicase domain, made up of two RecA-like domains, followed by an extended C-terminal domain (Fig