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Here are some symptoms of undermethylation to look out for: [22] Elevated homocysteine levels Depression Irritability Anxiety Multiple miscarriages Multiple chemical sensitivities Sensitivity to anesthetics Red face that lasts after exercising Allergies Being prone to addiction High libido Obsessive-compulsive disorder (OCD) Low pain threshold Headaches/migraines Digestive problems (such as IBS) Brain fog (especially after protein-rich meals) Insomnia High estrogen levels/estrogen dominance Low energy/fatigue Muscle pain Low levels of neurotransmitters (dopamine, norepinephrine, and serotonin) Heavy menstrual periods with blood clots Flakey skin rash under your nose* Lowered immunity* *Although I havent seen this in the research, its been an observation for me personally, as well as for a few clients, that difficulty fighting off viral infections as well as having a red rash under the nose, seems to correlate with poor methylation

Singh M, Verma Y, Rana SVS (2022) Attributes of oxidative stress in the reproductive toxicity of nickel oxide nanoparticles in male rats

Abudu, Y

Each ingredient has been academically studied for its unique properties, and when combined, they provide researchers with opportunities to evaluate potential complementary pathways in controlled invitro environments