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A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer

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Long-Term Safety Questions and Research Gaps Limited Clinical Data Most clinical trials last 12 years

AOD-9604 (Anti-Obesity Drug 9604) is a 16-amino-acid synthetic peptide based on residues 176-191 of the C-terminal region of human growth hormone, with the N-terminal phenylalanine replaced by tyrosine to improve stability