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Psychiatry 26 , 58885898 (2021)

The thioredoxin-thioredoxin reductase system can function in vivo as an alternative system to reduce oxidized glutathione in Saccharomyces cerevisiae

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But even with current evidence, clinicians can feel reasonably confident in advising curcumin-based interventions as part of comprehensive oral disease management, aligning with patient preferences for natural remedies when appropriate