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For example, a study found that rotenone-induced microbiota dysbiosis is implicated in the pathogenesis of Parkinsons disease via the microbiota-gut-brain axis, and fecal microbiota transplant (FMT) alleviates systemic inflammation, intestinal inflammation, and barrier destruction, attenuating BBB impairment and neuroinflammation

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Also, incorporating longitudinally-aligned nanofibrous intra-luminal guidance channels could improve nerve regeneration and confirmed previous findings that reported topographical cues in multi-channels conduit supported SCs migration and axon extensions in vivo [39]

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