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As a result, it causes immune-mediated enteropathy, intestinal inflammation, followed by the atrophy of villi, crypt hyperplasia and increased infiltration by intraepithelial lymphocytes [11]

CiteSpace allows for data visualization by constructing citation networks and co-occurrence networks, presenting the structure, patterns, and distribution of scientific knowledge in a specific discipline or field ( 3 Results 3.1 Annual publications A total of 5,301 articles were included in the analysis

10 The intestine is the primary target organ

This could be because aberrant copper metabolism gradually accumulates from the liver into other tissues over time, primarily harming the cornea and nervous system