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These results suggest that S-palmitoylation of ATG2A does not impact its N-terminal-mediated association with the ER

As a complement to the LLC experimental pulmonary metastasis model, we generated an additional mouse model: B16-F10 (melanoma) cells were intravenously injected in IGF1R-deficient ( CreERT2 ) and Igf1r fl/fl mice to induce lung metastasis (Supplementary Fig

The lncRNA FERRIN, which is produced under conditions of glutamine starvation induced by the transcription factor ATF4, interacts with the RNA-binding protein hnRNPK, thereby promoting its binding to and stabilizing SLC7A11, and consequently promoting the proliferation of cancer cells [41]

Altered cellular metabolism is an important characteristic of macrophage polarization