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Methionine and the glutathione pathway Methionine serves as a precursor for cysteine and, subsequently, for glutathione, one of the most important intracellular antioxidants

Many researchers have focused on investigating the impact of ICB treatment on the interactions between immune cells and cancer cells in the tumor microenvironment (170, 183185), including the tertiary lymphoid structures (186190), as well as the T cell phenotypes in the peripheral circulation (191197)