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By contrast, non-viral vectors, including liposomes and polymeric nanoparticles, provide improved biocompatibility and lower immunogenicity, although often at the expense of reduced transfection efficiency (111)

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(The 503A Bulks List is a list of drug substances that the FDA has approved for compounding under section 503A of the Federal Food, Drug, and Cosmetic Act.) If the peptides meet the safety requirements, the committee will recommend reclassifying them onto this list, so they can then be legally prescribed and compounded