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Cell experiments had demonstrated that increased intracellular GSH significantly reduced the toxicity of CDCZA nanoparticles to Eca-109 cells, so the CDCZA/NAC group showed limited inhibition of tumor growth

The 3xTg-AD mouse bearing human mutations of APP, PS1 and tau also develop early apathy-like deficits, marked by a decrease in spontaneous motor activity (Pardossi-Piquard et al., 2016)