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Next, embryonic stem cells, derived from the inner cell mass of a blastocyst, are pluripotent and can differentiate into all somatic cell types [21]

For example, IGF-IR and ErbB3 were significantly upregulated in ovarian cancer cells resistant to the anti-ErbB2 mAb trastuzumab [116]

10.1021/jacs.1c01925 127 PancoeS

GBM cell lines LN18, LN229, T98, and U87 and sarcoma cell lines HT161 and TC32 were a gift from Thomas Graeber (University of California, Los Angeles)