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Additionally, Adiwidjaja PBPK model predicted that schisandrol B and schisantherin B could effectively inhibit CYP3A4-mediated metabolism of IM and bosutinib

ALA, a precursor to omega-3 fatty acids, possesses anti-inflammatory properties [34] and may modulate mitochondrial function [35]

In this work we compared these two structures, particularly their H sites, and analyzed the effect of GSH binding on the stability and mobility of both enzymes through MD simulations