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[DOI] [PMC free article] [PubMed] [Google Scholar] 303.Sparks JD, Sparks CE

doi: 10.3389/fendo.2025.1547020 55 YadavPMaliPC

5 However, in the presence of oxidative stress, the GSTP1-JNK complex dissociates, allowing for JNK activation and GSTP1 dimerization

Accordingly, when thioredoxin function is compromised by blocking expression of TrxR enzymes TrxR knockout embryos fail to survive beyond midgestation (reviewed in Conrad, 2009