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Compared to the Sham group, the LPS-induced ICH microenvironment significantly stimulated BV2 microglia to secrete multiple pro-inflammatory cytokines, including IL-6 and TNF-

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Philpot BD, Sekhar AK, Shouval HZ, Bear MF (2001)

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Spine, 28 , 18601868

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Therefore, it is possible that NNMT may regulate energy metabolism through other mechanisms, and that NAD + is not necessary for this regulatory process

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