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Moreover, scTS2/16 supports a six- to sevenfold increase in the yield of these organoids when cultured in collagen I hydrogels, both in 3D and 2D

Bax, a pro-apoptotic Bcl-2 family protein, resides in the cytoplasm and translocates to the mitochondria in response to apoptotic stimuli, where it facilitates the release of Cyt C (Shalini et al., 2015)