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According to a study by Ottaviani et al ., peroxidated squalene induces the inflammatory mediators, which may play a role in pathogenesis of acne vulgaris

Clin Endocrinol (Oxf) 2006;64:4449.ArticlePubMed 21

4g), consistent with the downregulation of PPARA and its target genes

Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins