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Computational de novo design and characterization of a four-helix bundle protein that selectively binds a nonbiological cofactor

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Injectable NAD+ allows practitioners to formulate precise dosing protocols with predictable plasma concentrations, making it easier to track response and adjust as needed

The practice has recently gained mainstream attention due to tech millionaire Bryan Johnsons extreme and public efforts to radically extend his lifespan through an intense regimen involving strict diets, over 100 supplements daily and experimental treatments like blood transfusions