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For example: People with gastrointestinal disorders (like Crohns disease or celiac disease) might need more B12 because they absorb less

However, to date, there are no in vitro models that simulate long-term neurovascular dysfunction, therefore, new data in this aspect are provided by cross-sectional observation results (Parkes et al

[16] Transport-mediated absorption and tissue delivery is a complex process involving three transport proteins: haptocorrin (HC), intrinsic factor (IF) and transcobalamin II (TC2), and respective membrane receptor proteins (Figure)