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200 A randomized placebo-controlled trial involving 75 subjects with fibromyalgia found 100 mg of oral magnesium (as magnesium chloride) once daily for one month improved scores on the Depression Anxiety Stress Scale and reduced pain severity in a subgroup of participants with mild-to-moderate stress, but had no effect on symptom parameters in those with severe-to-extremely severe stress

With the exception of red blood cells, cells have a nucleus which holds the genetic information as DNA to enable them to split and make copies, and mitochondria where chemical reactions take place to release energy

Because of their close interdependence the absence of one of these B vitamins will impair the action of the others

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