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In this study, we demonstrated that cystine decreased the intracellular GSH/GSSG ratio in Salmonella , which disrupted cellular redox homeostasis, increased ROS production, and activated the Fenton reaction, thereby enhancing the bactericidal effect of gentamicin on drug-resistant bacterial strains

Microbiome dysbiosis disrupts iron homeostasis and reduces the production of antioxidant metabolites such as short-chain fatty acids (SCFAs) and bile acids (BAs), thereby exacerbating systemic and local ovarian oxidative stress