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doi: 10.1016/j.cell.2009.12.017 116 SaitouMBartonSCSuraniMA

Moreover, nitric oxide is produced in hypoxic conditions in a respiratory chain reaction, and RNS may trigger reactive species production, such as reactive aldehydes, malondialdehyde (MDA) and 4-hydroxy-2-non-enal (Hussain et al., 2016)