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Dual inhibition of GGCT and xCT enhances antitumor efficacy in vivo without systemic toxicity To evaluate the therapeutic efficacy of dual GGCT and xCT inhibition in glioblastoma, we orthotopically implanted U87MG cells into the cerebral cortex of immunodeficient mice and treated them with pro-GA, the xCT inhibitor imidazole ketone erastin (IKE), or their combination

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Canadian Network for Mood and Anxiety Treatments (CANMAT) 2023 Update on Clinical Guidelines for Management of Major Depressive Disorder in Adults: Rseau canadien pour les traitements de lhumeur et de lanxit (CANMAT) 2023 : Mise jour des lignes directrices cliniques pour la prise en charge du trouble dpressif majeur chez les adultes

Purification of proteins fused to maltose-binding protein