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To support this idea, these studies found that increasing muscle carnitine content saves muscle glycogen during low-intensity exercise (consistent with an increase in muscle lipid utilization), but that increasing muscle carnitine content reduces muscle anaerobic ATP production during high-intensity exercise by better matching glycolytic, pyruvate dehydrogenase complex, and mitochondrial flux [23]

This genetic variation is estimated to affect 1 in 350 males in the United States

Thus, the glycolysis pathway would be downregulated and gluconeogenesis would be upregulated

Effect of Acute l-Carnitine Supplementation on Blood Lactate, Glucose, Aerobic and Anaerobic Performance in Elite Male Artistic Gymnasts