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The better option depends on the condition being treated

doi: 10.1016/0003-2697(89)90121-8

This would be the case if the glutathione molecule was substantially modified structurally (i.e., chemically), so that it would no longer be regarded as a dietary supplement by the Food and Drug Administration

Interaction of SARS-CoV-2 proteins with specific host cellular targets could rewire sugar-, AA-, FA-, as well as nucleotide-metabolism(s), and distinctly alter or impair bioenergetics, immune response, and redox homeostasis in the human body, thereby facilitate viral life cycle 21,22