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Trends Biotechnol 2011

23 It also binds to glutathione peroxidase to reduce production of lipid peroxide

The novel object recognition test was carried out 24 hours after last dose of drugs: MIR (10 mg/kg, i.p.) and aripiprazole (0.1 and 0.3 mg/kg, i.p.)

The study concludes that CHAC1 is a novel UPR target gene negatively regulated by CHOP, revealing complex regulatory crosstalk in the UPR pathway and providing insights into the molecular mechanisms of oxidative stress and cell death (Nomura et al., 2020)