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Cell 140:951

Interestingly, PMNs expressing a kinase-deficient PI3K can still undergo oxidative burst, but fail to produce ROS when the ATP-binding site of this protein is blocked by inhibitors (Kulkani et al., 2011)

For example, the RFD directs DNMT1 to replicate DNA, while the CXXC domain recognizes and binds DNA containing unmethylated CpG sites

In contrast to radioprotection, a recent study showed that ebselen in combination with -radiation synergistically radio-sensitized the MCF7 cells of breast cancer origin (Table 2) [60]