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These data suggest that IPA-mediated amelioration of intestinal injury may primarily operate through barrier restoration rather than significant modulation of these specific immune parameters at the examined time points

Culmination of Evidence That IGF-IR Represents A Clinically Important Therapeutic Target in TAO To test the central hypothesis that IGF-IR represents not only a critical component in the pathogenesis of TAO, but can also be therapeutically targeted, two placebo-controlled, multicenter clinical trials of teprotumumab have been conducted (123, 124)

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Diabetes 70, 24312443