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FDA's evaluation concluded that the criteria weighed against placement on the list, citing inadequate physicochemical characterization, immunogenicity concerns from impurities and aggregates, lack of clinical effectiveness data for any approved use, and absence of published human exposure data for the proposed subcutaneous and topical routes

Many are unsure if they are at risk of a vitamin B12 deficiency, if you are wondering if you are or what the symptoms may be to look out for, individuals with a vitamin B12 deficiency may include: Elderly Anyone who may have had previous surgery that included removing part of the bowel that absorbs vitamin B12 Any individual on metformin for diabetes Anyone that is following a strict vegan diet Anyone taking long-term antacid medication for heartburn What is Vitamin B12